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Targeted Cancer Treatment in Silico

Publisher: 
Birkhäuser
Number of Pages: 
227
Price: 
69.99
ISBN: 
9781461483007
Date Received: 
Monday, December 30, 2013
Reviewable: 
No
Include In BLL Rating: 
No
Natalia L. Komarova and Dominik Wodarz
Series: 
Modeling and Simulation in Science, Engineering and Technology
Publication Date: 
2013
Format: 
Hardcover
Category: 
Monograph
Tags: 

Background and Scope of the Book.- Part I Treatment of Cancer with Small Molecule Inhibitors.- An Introduction to Small Molecule Inhibitors and Chronic Myeloid Leukemia.- Basic Dynamics of Chronic Myeloid Leukemia During Imatinib Treatment.- Stochastic Modeling of Cellular Growth, Treatment, and Resistance Generation.- Evolutionary Dynamics of Drug Resistant Mutants in Targeted Treatment of CML.- Effect of Cellular Quiescence on the Evolution of Drug Resistance in CML.- Combination Therapies: Short term versus Long term Strategies.- Cross Resistance: Treatment and Modeling.- Mathematical Modeling of Cyclic Cancer Treatments.- Part II Treatment of Cancer with Oncolytic Viruses.- Introduction to Oncolytic Viruses.- Basic Dynamics of Oncolytic Viruses.- Mitotic Virus Transmission and Immune Responses.- Axiomatic Approaches to Oncolytic Virus Modeling.- Spatial Oncolytic Virus Dynamics.- Oncolytic Viruses and the Eradication of Drug-resistant Tumor Cells.

Publish Book: 
Modify Date: 
Monday, December 30, 2013

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