From the Biological ESTEEM collection
This worksheet simulates the molecular evolution of DNA sequences. The program begins with a single (random) sequence, then follows that sequence through time as it reproduces and mutates. Eventually, up to 20 evolutionary related sequences are generated. EvolSeq then calculates the genetic distances between each pair of DNA sequences, and also between the associated amino acid sequences. Note that this file requires that "macros" are enabled in Microsoft Excel.
This module is accompanied on the download site by documentation (in .pdf format) on the use of the Excel worksheet in the classroom.
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