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Luria-Delbruck

Author(s): 
Tony Weisstein, John R. Jungck, Doug Green

From the Biological ESTEEM collection

ESTEEM Category

Evolution

Description

These two workbooks model the evolution of phage resistance in a bacterial population under two alternative hypotheses. Under the hypothesis of acquired immunity, mutation produces some resistant bacteria even in the absence of phage; this resistance can be passed to their offspring. Under the mutation hypothesis, by contrast, mutation produces some resistant bacteria even in the absence of phage; again, this resistance can be passed to their offspring. Predictions of the two models can be compared to each other and to actual data. 

Editor's note:

See the documentation (in .pdf format) provided on the module site for instructions on using the downloaded workseets.

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Tony Weisstein, John R. Jungck, Doug Green, "Luria-Delbruck," Convergence (December 2006)