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Multiple Alignment

Author(s): 
Tony Weisstein, Peter Lockhart

From the Biological ESTEEM collection

ESTEEM Category

Sequence Alignment

Description

These two worksheets implement a dynamic programming algorithm for simultaneous alignment of multiple sequences. The user inputs three sequences and sets scoring parameters for matches, mismatches, and gaps; the worksheet then calculates the optimal 3D trace-back path and displays the optimal alignment. Separate worksheets are available for global and local alignment.

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Tony Weisstein, Peter Lockhart, "Multiple Alignment," Convergence (December 2006)