Author(s):
Peter Lockhart, Tony Weisstein
From the Biological ESTEEM collection
ESTEEM Category
Sequence Alignment
Description
These two worksheets implement a dynamic programming algorithm for pairwise sequence alignment. The user inputs three sequences and sets scoring parameters for matches, mismatches, and gaps; the worksheet then calculates the optimal trace-back path, from which the user can determine the optimal alignment. Separate worksheets are available for global and local alignment.
Editor's Note
The documentation provided on the download site consists of a 29-page draft chapter (in .pdf format) on Sequence Alignment.
Go to the Sequence Alignment module in a new window
Peter Lockhart, Tony Weisstein, "Pairwise Alignment," Convergence (December 2006)